Unfortunately, the additional stress and worry caused by the global pandemic is only contributing to the crisis.
The World Health Organisation says stress is the health epidemic of the 21st Century. This is because as humans we are much more susceptible to diseases, viruses, bad bacteria, and mental health problems when we are stressed.
THE STRESS HORMONE CORTISOL SHUTS DOWN THE IMMUNE SYSTEM MAKING US VULNERABLE TO VIRUSES, DISEASE, INFECTION, AND POOR MENTAL HEALTH.
There is evidence that higher cortisol and stress levels can activate - and reactivate - a number of viruses.
Even more importantly, there is evidence that T-cells are influenced by cortisol responses to viral infections.
SARS research - which is a good model for the current coronavirus COVID-19 - demonstrates that depleted CD4 T-cells gives higher replication of the virus and a greater viral disease effect.
There is also evidence to suggest that outcomes in SARS in humans were directly related to a T-cell response, and cortisol interferes with this process.
It makes sense on many levels to reduce cortisol as the #1 way to be resistant to coronavirus.
Of course, there are drug companies researching ways to reduce viral load, reduce community infection rates, and potentially improve severity of disease - all by targeting cortisol.
There is also a post SARS syndrome where people infected have cognitive defects and this links to persistent low cortisol.
It may be that during such virus infection, people have a hyper response to cortisol (stress response) which then blunts cortisol during recovery.
It may be that managing cortisol also manages any post cognitive effects due to a brain pituitary axis disturbance providing some protection.
Of course, here at Health Evolution we are not a drug company and so we cannot and do not make any claims to treat, cure, prevent, or diagnose any disease.
We do, however, provide products proven to manage cortisol, the stress hormone.
Proven for more than 90 years, with no side effects.
Because our formulas use YTE® which is a rare, all-natural ingredient, our raw ingredients cost is high, whereas a drug company is looking for a cheap chemical fix.
There is no drug currently available to safely manage cortisol.
But Health Evolution formulas do manage cortisol, with clinical trials to prove it.
The links between out-of-control cortisol and disease, virus infection, and poor mental health are all clinically proven.
YTE® AT RECOMMENDED CLINICAL DOSE IS THE #1 WAY TO MANAGE OUT-OF-CONTROL CORTISOL, THE STRESS HORMONE WHICH DESTROYS IMMUNITY
WE ARE FACING THE "PERFECT STORM" OF AN EPIDEMIC COMBINED WITH A PANDEMIC.
The World Health Organisation says stress is the health epidemic of the 21st Century and novel coronavirus COVID-19 is the "unchartered territory" pandemic.
COVID-19 is the pandemic mainly affecting people who are chronically stressed, which appears to be why babies and children are less affected.
Stress hormones shut down the immune system making us vulnerable to viruses, disease, infection, and poor mental health.
Do you struggle with any of these issues:
- Low Energy
- Inflammation
- Trouble sleeping
- Slow metabolism
- Constant worrying
- Stubborn weight gain
- Anxiety and overwhelm
- Lack of clarity and focus
- Low mood and tiredness
- Poor memory and brain fog
- Cravings and poor digestion
- Cuts and wounds slow to heal
Every one of these symptoms has been linked with out of control cortisol, a condition also known as chronic stress and “allostatic load”.
Now more than ever it is essential to modulate your cortisol levels.
High-stress leads to high cortisol levels ... which leads to high-stress.
It's essential to break the cycle to achieve a strong immune system, naturally and quickly.
WHAT IS CHRONIC STRESS?
Simply when our bodies don't recover from one stress factor before another piles on, and another, and another ...
Our body and brain both react to be hyper-vigilant and "ready to run".
But we don't respond in ways to alleviate the stress before another stress trigger comes in ... so our heart rate is higher, our mind is racing, we're "wired" ... and over time that dulls into constant fatigue and overwhelm.
Because our brains and bodies are overworked, poor physical and mental health result. Including vulnerability to viruses.
THERE ARE THREE WAYS WE CAN BE CHRONICALLY STRESSED:
Physical: trauma, injury, accident or fall
Chemical and biological: viruses, flu, infection, hangovers, unbalanced blood sugar levels, toxic loads from processed food, environmental chemicals
Emotional: fear, work or business pressure, financial problems, family tragedies, inherited trauma, exposure to negative news and constant advertising.
When chronically stressed, our body and brain are on constant high alert, in fight or flight mode, and therefore other "housekeeping" tasks are shut down. Including complex tasks such as proper digestion, healing, immunity, relaxation, and restorative sleep.
To support the immune system naturally and quickly, forget so-called immune system supplements like vitamins B, C, D, E, zinc, magnesium, probiotics, prebiotics, colloidal silver, saunas, and all the rest ... taking these without addressing cortisol levels is like driving with one foot on the gas (accelerator) and the other stamped down hard on the brake.
You're going nowhere fast and just burning fuel and rubber. Wearing out the engine and all the moving parts.
That's why you MUST get your cortisol under control, first.
That's why our formulas are called the foundational formulas.
TeloMind and AminoBoosters have full recommended clinical dose YTE®. This 
1600mg/daily dose manages and modulates your cortisol naturally, safely, and quickly.
In addition, we strongly recommend taking AminoSerene as a supplementary formula.
YTE® uniquely contains all the amino acids in perfect natural balance and at the recommended clinical dose. The supplement AminoSerene also contains the entire B vitamin complex at the recommended clinical dose.
Vitamin B6 and B12 in particular are recommended as immune system supplements - but they only work their best when all the B vitamin complex is present, and when bioavailable forms are used.
We only use the most bioavailable forms of the entire B vitamin complex, including MecobalActive® B12.
Most supplements use cheap versions which simply don't work.
Taking Health Evolution supplements have been shown to correspond with longer telomeres, and a younger biological age.
Why is this important? A newborn baby’s telomeres can be around 10,000 bases in length, as compared with 3,000 in adults and only 1,500 in the elderly.
After the newborn phase, the number of base pairs tends to decline by approximately 20 to 40 per year. For example, by the time a person reaches the age of 40, their telomeres could have lost up to 1,600 base pairs. However, aging is not the only factor associated with telomere shortening; other factors such as smoking, poor nutrition, and obesity also affect telomere length. (Source: News-medical.net & Yale Medicine. Telomere Research, 2019 https://www.yalemedicine.org/conditions/telomere-research, and UCSF.edu Scientists Report – Lifestyle Changes May Lengthen Telomeres, A Measure of Cell Aging https://www.ucsf.edu)
THE #1 WAY TO SUPPORT IMMUNITY IS TO BALANCE CORTISOL
Right now, it's crucial the entire population increases immunity.
The trouble is, the W.H.O. - the World Health Organisation - identified chronic stress as "the health epidemic of our time". Coupled with the COVID-19 coronavirus pandemic, chronic stress kills by dramatically decreasing immunity.
Now, you can not only feel the difference when stress is gone, you can prove it.
The unique DNA-test lets you measure your success, by measuring the length of your telomeres to determine your biological age versus your chronological age.
The good news is you can change the length of your telomeres. The fastest way to do so is to move from a chronically stressed state of excess cortisol.
Health Evolution clinical dose P.L.A.N. - Pure Live Active Nutrition - formulas are the only 60-second-a-day way to modulate cortisol, the stress hormone, while at the same time regenerating stem cells.
WHAT DOES THE TELOMERE TEST MEASURE?
Tracks your cellular age based on your telomere length
The test is based on a simple at-home blood test
Why measure?
Yes, people can change their telomeres with a healthier lifestyle.
Our customers are already doing exactly that.
Check out Michelle, who went from biological age 82 to 53 in just six months - and the ONLY thing Michelle did differently was taking our formula.
Michelle is actually aged 49 in chronological years but suffers a chronic incurable disease: with our supplements, she's able to keep her job, reduce how old she felt - and how old her body said she was - by a staggering nearly 30 years!
We are so confident in the results of our products, we make it easy for you to prove it to yourself.
Simply arrange your telomere test and then take your supplements every day.
Take another telomere test after 6 months of positive changes, and see the results.
Results are so motivating - now as well as feeling the difference, you can see the evidence.
GET YOUR TELOMERE TEST: THE DETAILS
Get Your Telomere Test here:
https://healthevolutionproject.com/product-category/telomere-tests/
The P.L.A.N. Pure Live Active Nutrition YTE® formulas are brought to you by Health Evolution, a privately held science-based dietary supplements company founded by health and research advocates, advised by world-famous medical specialists.
The telomeres genetic test is brought to you by Telomere Diagnostics Inc., a privately held molecular testing company founded by a group of scientists including the winner of the 2009 Nobel Prize in Medicine for her work in telomere biology.
We arrange the test for you within 24 hours of purchase, and can arrange the follow up in 6 months' time.
READY TO GET STARTED
Combining the only source of P.L.A.N. Formulas: Pure Live Active Nutrition with Young Tissue Extract Dynamic Protein YTE®. Health Evolution provides four supplements of personalised life-changing nutrition, for professionals who expect more.
The only 60-second-a-day way to modulate cortisol, the stress hormone, while at the same time regenerating stem cells.
So you can not only feel the difference when stress is gone, you can prove it.
THE #1 WAY TO SUPPORT IMMUNITY IS TO BALANCE CORTISOL
Right now, it's crucial to support and maintain immunity.
The trouble is, the W.H.O. - the World Health Organisation - identified chronic stress as "the health epidemic of our time".
Coupled with the COVID-19 coronavirus pandemic, chronic stress kills by dramatically decreasing immunity.
NOW, YOU CAN NOT ONLY FEEL THE DIFFERENCE WHEN STRESS IS GONE, YOU CAN PROVE IT
The unique DNA-test lets you measure your success, by measuring the length of your telomeres to determine your biological age versus your chronological age. The good news is you can change the length of your telomeres with lifestyle and diet changes.
If you have questions, give us a call on (225) 442-9766, contact us here, or arrange to speak with Co-founder & Head of Research Angela Wright MBE personally by scheduling a call at calendly.com/angelawright
Place your order today:
SOURCES:
Cortisol and Cognition
Midlife stress alters memory and mood-related behaviors in old age: Role of locally activated glucocorticoids
Psychoneuroendocrinology 89 (2018) 13–22. Nicola Wheelan, Christopher J. Kenyon, Anjanette P. Harris, Carolynn Cairns, Emad Al Dujaili, Jonathan R. Seckl, Joyce L.W. Yau (2018)
11β-hydroxysteroid dehydrogenase inhibition improves cognitive function in healthy elderly men and type 2 diabetics
PNAS, 101(17), 6734-6739. Sandeep, T. C., Yau, J. L. W., MacLullich, A. M. J., Noble, J., Deary, I. J., Walker, B. R., & Seckl, J. R. (2004).
Cognitive and disease-modifying effects of 11β-hydroxysteroid dehydrogenase type 1 inhibition in male Tg2576 mice, a model of Alzheimer’s disease
Endocrinology, 1-12. Sooy, K., Noble, J., McBride, A., Binnie, M., Yau, J. L. W., Seckl, J. R., Walker, B. R., & Webster, S. P. (2015).
Inhibiting 11β-hydroxysteroid dehydrogenase type 1 prevents stress effects on hippocampal synaptic plasticity and impairs contextual fear conditioning
Journal of Neuroscience, 31(11), 4188 – 4193. Yau, J. L., Noble, J., & Seckl, J. R. (2011).
Journal of Neuroscience, 31(4), 5406-13. Mohler, E. G., Browman, K. E., Roderwald, V. A., Cronin, E. A., Markosyan, S., Scott Bitner, R., Strakhova, M. I., Drescher, K. U., Hornberger, W., Rohde, J. J., Brune, M. E., Jacobson, P. B., & Rueter, L. E. (2011).
Journal of Neuroscience, 30(20), 6916-20. Holmes, M. C., Carter, R. N., Noble, J., Chitnis, S., Dutia, A., Paterson, J. M., Mullins, J. J., Seckl, J. R., Yau, J.L. (2010).
Journal of Neuroscience, 30(41), 13867-13872. Sooy, K., Webster, S. P., Noble, J., Binnie, M., Walker, B. R., Seckl, J. R., & Yau, J. L. W. (2010).
Endocrinology, 1-12. Sooy, K., Noble, J., McBride, A., Binnie, M., Yau, J. L. W., Seckl, J. R., Walker, B. R., & Webster, S. P. (2015).
British Journal of Pharmacology. Scott P Webster, AndrewMcBride, Margaret Binnie, Karen Sooy, Jonathan R Seckl, Ruth Andrew, T David Pallin, Hazel J Hunt, Trevor R Perrior, Vincent S Ruffles, J William Ketelbey, Alan Boyd and Brian R Walker (2017).
Bioorganic & medicinal chemistry letters, 17(10), 2838-2843. Webster, S. P., Ward, P., Binnie, M., Craigie, E., McConnell, K. M., Sooy, K., Vinter, A., Seckl, J.R. & Walker, B. R. (2007).
Endocrinology, 1-12. Sooy, K., Noble, J., McBride, A., Binnie, M., Yau, J. L. W., Seckl, J. R., Walker, B. R., & Webster, S. P. (2015).
British Journal of Pharmacology. Scott P Webster, AndrewMcBride, Margaret Binnie, Karen Sooy, Jonathan R Seckl, Ruth Andrew, T David Pallin, Hazel J Hunt, Trevor R Perrior, Vincent S Ruffles, J William Ketelbey, Alan Boyd and Brian R Walker (2017).
Bioorganic & medicinal chemistry letters, 17(10), 2838-2843. Webster, S. P., Ward, P., Binnie, M., Craigie, E., McConnell, K. M., Sooy, K., Vinter, A., Seckl, J.R. & Walker, B. R. (2007).
Of course there are many research papers and reports regarding how chronic stress shortens telomeres.
Clinical evidence demonstrates how YTE® in particular, additionally supported by other ingredients in our formulas, modulates cortisol, the "stress hormone", positively impacting the reduction of chronic stress, and positively affecting telomeres.
HOW CHRONIC STRESS SHORTENS TELOMERES AND HOW REDUCING CHRONIC STRESS LENGTHENS TELOMERES:
As reported in the American Institute of Stress:
"STRESS, AGING, AND TELOMERES"
All the cells in our body contain tiny clocks called telomeres that can determine how long they will live.
Telomeres are little caps at the end of chromosomes that prevent loss or injury to genetic information during cell division. Each time a cell divides, part of the telomere is lost and it becomes shorter.
When a telomere eventually disappears because of repeated cell divisions, chromosomal damage prevents the cell from accurately reproducing itself. This shortening and eventual erosion of telomeres are prevented or reduced by telomerase, an enzyme in cells that preserves their length.
Many believe that telomere destruction and reconstruction is related to the balance between aging and cancer and explains why cancer is more common in the elderly.
In the illustration to the left, chromosomes are stained blue and the protective telomere caps at their ends are stained yellow. Cells with long telomeres live longer. Short telomeres have been linked to a wide range of human diseases, including coronary heart disease, osteoporosis, and HIV infection. Shortening of telomeres is prevented or reduced by telomerase, which has been shown to keep immune cells young by preserving their length and ability to continue to divide and reproduce accurate replicas.
UCLA researchers recently confirmed prior reports that people subjected to chronic stress tended to have shorter telomeres. They have now uncovered a mechanism that explains how stress causes telomere shortening, which could lead to breaking the well-known links between stress and heart disease, as well as accelerated aging. Cells with long telomeres live longer. Short telomeres have been linked to a wide range of human diseases, including coronary heart disease, osteoporosis, and HIV infection. Shortening of telomeres is prevented or reduced by telomerase, which has been shown to keep immune cells young by preserving their length and ability to continue to divide and reproduce accurate replicas.
Chronic stress results in increased secretion of cortisol that causes a rise in blood sugar and blood pressure and reduces inflammation and immune system resistance to infection. However, this new study shows that cortisol also suppresses telomerase activation in immune system cells so that telomeres are no longer protected during cell division and become progressively shorter. This leads to early cell aging and distorted replicas of the original cell that could lead to cancer and other diseases. As the lead author noted in an interview, “We are testing therapeutic ways of enhancing telomerase levels to help the immune system ward off cortisol’s effect. If we’re successful, one day a pill may exist to strengthen the immune system’s ability to weather chronic emotional stress.”"
This study was approved by the UCLA Institutional Review Board:
Choi J. Fauce SR, Effros RB. Reduced telomerase activity in human T lymphocytes exposed to cortisol. Brain Behavior and Immunity May 2008; 22:600-605 - https://www.ncbi.nlm.nih.gov/pubmed/18222063 - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386249/
Telomere, Telomerase, and Chronic Stress:
- Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age.[J Immunol. 2000]
- [Telomerase activity and telomere length in CD4+,CD8+ and CD19+ lymphocytes from patients with systemic lupus erythematosus].[Zhejiang Da Xue Xue Bao Yi Xue...]
- An antiapoptotic role for telomerase RNA in human immune cells independent of telomere integrity or telomerase enzymatic activity.[Blood. 2014]
- Telomerase induction in T cells: a cure for aging and disease?[Exp Gerontol. 2007]
- Tales of tails: regulation of telomere length and telomerase activity during lymphocyte development, differentiation, activation, and aging.[Immunol Rev. 1997]
- Fetal Membrane Architecture, Aging and Inflammation in Pregnancy and Parturition[Placenta. 2018]
- Sex-specific effects of the in ovo environment on early-life phenotypes in eiders[Oecologia. 2019]
- Differential gene expression profile analysis in corticosterone-treated PC12 cells[International Journal of Clini...]
- The relationship between neighborhood socioeconomic deprivation and telomere length: The 1999–2002 National Health and Nutrition Examination Survey[SSM - Population Health. 2019]
- Impact of continuous predator threat on telomere dynamics in parent and nestling pied flycatchers[Oecologia. 2019]
- Reduced telomerase activity in human T lymphocytes exposed to cortisol
Reduced telomerase activity in human T lymphocytes exposed to cortisol
NIHPA Author Manuscripts. 2008 May; 22(4)600 - Reduced telomerase activity in human T lymphocytes exposed to cortisol.
Reduced telomerase activity in human T lymphocytes exposed to cortisol.
Brain Behav Immun. 2008 May;22(4):600-5. doi: 10.1016/j.bbi.2007.12.004. Epub 2008 Jan 25.
- Review The role of CD8+ T-cell replicative senescence in human aging.[Immunol Rev. 2005]
- Interspecies variations of corticosteroid-binding globulin parameters.[Domest Anim Endocrinol. 1996]
- Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus.[Clin Immunol. 2002]
- Review Telomerase in T lymphocytes: use it and lose it?[J Immunol. 2007]
- Review The role of CD8+ T-cell replicative senescence in human aging.[Immunol Rev. 2005]
- Accelerated telomere shortening in response to life stress.[Proc Natl Acad Sci U S A. 2004]
- Cutting edge: telomerase activation in human T lymphocytes does not require increase in telomerase reverse transcriptase (hTERT) protein but is associated with hTERT phosphorylation and nuclear translocation.[J Immunol. 2001]
- The flow cytometric analysis of telomere length in antigen-specific CD8+ T cells during acute Epstein-Barr virus infection.[Blood. 2001]
- Telomerase regulation during entry into the cell cycle in normal human T cells.[Mol Biol Cell. 1996]
- Accelerated telomere shortening in response to life stress.[Proc Natl Acad Sci U S A. 2004]
- Cell aging in relation to stress arousal and cardiovascular disease risk factors.[Psychoneuroendocrinology. 2006]
- Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients.[J Immunol. 2007]
- Glucocorticoids attenuate T cell receptor signaling.[J Exp Med. 2001]
- Genetic manipulation of telomerase in HIV-specific CD8+ T cells: enhanced antiviral functions accompany the increased proliferative potential and telomere length stabilization.[J Immunol. 2004]
- Review Telomerase in T lymphocytes: use it and lose it?[J Immunol. 2007]
- Review The role of CD8+ T-cell replicative senescence in human aging.[Immunol Rev. 2005]
- Divergent telomerase and CD28 expression patterns in human CD4 and CD8 T cells following repeated encounters with the same antigenic stimulus.[Clin Immunol. 2002]
- Review Is immunosenescence infectious?[Trends Immunol. 2004]
- Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals.[J Virol. 2001]
- Review Is immunosenescence infectious?[Trends Immunol. 2004]
- Immune responses and latent herpesvirus reactivation in spaceflight.[Aviat Space Environ Med. 2001]
- Reactivation and shedding of cytomegalovirus in astronauts during spaceflight.[J Infect Dis. 2000]
- Review Why aging T cells fail: implications for vaccination.[Immunity. 2006]
- Progression to AIDS, a clinical AIDS condition and mortality: psychosocial and physiological predictors.[Psychol Med. 2002]
- Accelerated telomere shortening in response to life stress.[Proc Natl Acad Sci U S A. 2004]
- Accelerated telomere erosion is associated with a declining immune function of caregivers of Alzheimer's disease patients.[J Immunol. 2007]
- Chronic stress alters the immune response to influenza virus vaccine in older adults.[Proc Natl Acad Sci U S A. 1996]
- Review Stress-induced immunomodulation: impact on immune defenses against infectious disease.[Biomed Pharmacother. 2000]
Link to the Science pages:
- regarding YTE®
- regarding the other ingredients in our formulas
Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms relat...
Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
The cumulative cost of additional wakefulness: dose-response effects on neurobeh...
The cumulative cost of additional wakefulness: dose-response effects on neurobehavioral functions and sleep physiology from chronic sleep restriction and total sleep deprivation.
The Effects of Powdered Fertilized Eggs on Depression
The Effects of Powdered Fertilized Eggs on Depression
Place your order now and see the difference it can make, either ordering one of our stand-alone supplements or the Ultimate Health & Immunity 30 Day System, here:
Health Evolution and/or Telomere Diagnostics are not intended for screening, diagnosing, treating or preventing diseases or medical conditions. The sites do not offer medical advice and nothing contained in the content is intended to constitute professional advice for medical diagnosis. Results may indicate the possibility of identifying a rare telomere syndrome associated with extremely shorter or longer average telomere length (ATL). In these rare cases, further testing and consultation with a doctor to rule in or rule out a telomere syndrome is recommended. Telomeres testing is available for individuals between the ages of 20 to 80 within the United States, except for the state of New York, and elsewhere by arrangement. The information provided should not be used to replace medically appropriate screening tests recommended based upon actual age or other risk factors, nor should the information be used to make decisions about diagnosis or treatment of diseases or medical conditions. The Diagnostics lab is regulated under the Clinical Laboratory Improvement Amendments of 1988 (CLIA) as qualified to perform high complexity clinical testing with performance characteristics determined by Telomere Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration.
